Adult
PO
Allergic and inflammatory disorders: 5-60 mg/day, in 2-4 divided doses.
Rheumatoid arthritis. Initial: 5-7.5 mg/day, adjust dose if needed.
Multiple sclerosis 200 mg/day for 1 wk, then 80 mg every other day for 1 mth.

IV/IM
Allergic and inflammatory disorders - Na phosphate ester: 5-60 mg prednisolone base/day.

Ophth
Conjunctivitis - 0.12 or 1% acetate susp: instill 1-2 drops 2-4 times/day. Higher frequency may be used during the initial 24-48 hr. Re-evaluate if there is no improvement after 2 days of treatment.

Otic
Allergic and inflammatory conditions of the ear - 0.5 or 1% acetate or phosphate soln: instill as directed.

Intra-articular joint inflammations - acetate: 5-25 mg; - phosphate: 2-30 mg; - terbutate:4-40 mg.

Topical
Rheumatoid arthritis - farnesylate: apply to the affected area as necessary.

Adverse drug reactions: Cushing's syndrome and growth retardation in children, osteoporosis, fractures, peptic ulceration, glaucoma, cataracts; hyperglycaemia, pancreatitis; increased appetite, obesity.

Adapted from CIMS Drug Information System. Internet. Accessed on January 10, 2016.