Injection of neurolytic solutions and/or steroids directly into a bone where metastases are producing pain not responsive to radiotherapy.

This invasive procedure was more popular in the late 20th century than it is today. It was used in easily accessible bones, such as the ribs, sternum, anterior surface of tibia, iliac crest, and pubic symphysis.
Successful and immediate analgesia lasting up to 8 weeks was reported using methylprednisolone sodium succinate with or without long-acting local anesthetic and/or 1% phenol.

Derek Doyle, personal communication.