The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity.
Escitalopram selectively inhibits CNS neuronal re-uptake of serotonin (5-HT) and potentiates serotonergic activity.
It has minimal effects on norepinephrine and dopamine neuronal re-uptake.
Adult
PO
Depression; obsessive compulsive disorder; anxiety: 10 mg once daily, increased if necessary. Max: 20 mg daily.
Panic disorder. Initially, 5 mg daily, increased to 10 mg daily after 7 days. Max: 20 mg daily.
Elderly: half the adult dose. Hepatic impairment: dosage adjustments may be required.
