What is Citalopram hydrobromide - Meaning and definition

Published by Roberto Wenk. Reviewed by Alison Ramsey. Last updated date: October 29, 2018.

The orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), citalopram selectively inhibits the central nervous system (CNS) neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the CNS. This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA).

National Cancer Institute. NCI Drug Dictionary. Internet. September 15, 2009.

Published by Roberto Wenk. Last updated date: February 8, 2016.

Adult, PO
Depression; depressive phase of bipolar disorder. Initial: 20 mg/day, increased to max 40 mg/day after at least 1 wk.
Panic disorder. Initial: 10 mg/day, increased to 20 mg/day after 1 wk.

Indications in palliative care
Can be useful in the treatment of painful diabetic neuropathy.
Can be tried as adjuvant analgesic for pain in patients with advanced disease.

Adapted from CIMS Drug Information System. Internet. Accessed on January 10, 2016.

Citalopram hydrobromide

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