What is Buspirone hydrochloride - Meaning and definition

Published by Roberto Wenk. Last updated date: February 8, 2016.

The hydrochloride salt of an anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs.
Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems.
Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects.

National Cancer Institute. NCI Drug Dictionary. Internet. September 15, 2009.

Published by Roberto Wenk. Last updated date: February 8, 2016.

Adult, PO
Initial: 5 mg 2-3 times/day, may increase gradually if needed. Max: 45 mg/day in divided doses.

Adverse drug reactions: dizziness, nausea, headache, nervousness, lightheadedness, excitement, paraesthesia, sleep disturbances, chest pain, tinnitus, nasal congestion, sore throat. Less sedation and lower potential for dependence compared to other anxiolytics.

CIMS Drug Information System. Internet. Accessed on January 10, 2016.

To cite

Buspirone hydrochloride. IAHPC Pallipedia. https://pallipedia.org/buspirone-hydrochloride. Accessed