A benzodiazepine mainly used to treat anxiety or panic states. Bromazepam may be also used as hypnotic medication or to mitigate withdrawal effects of alcohol consumption. After its nightime administration, a highly significant reduction of gastric acid secretion occurs during sleep followed by a highly significant rebound in gastric acid production the following day.

Bromazepam binds to the GABA receptor, causing a conformational change and increasing the inhibitory effects of GABA. It acts as a positive modulator, increasing the receptors' response when activated by GABA itself or an agonist (alcohol).

It is an intermediate-acting benzodiazepine metabolized hepatically via oxidative pathways; it does not possess any antidepressant or antipsychotic qualities.

Bromazepam is similar in side effects to other “classical” benzodiazepines, such as diazepam, clonazepam, oxazepam, lorazepam, nitrazepam, flurazepam, and clorazepate. The most common side effects reported are drowsiness, sedation, ataxia, memory impairment, and dizziness.
Prolonged use of bromazepam can cause tolerance and may lead to both physical and psychological dependence on the drug.

See reference for more information.

Adapted from Wikipedia, the free encyclopedia. Internet. Accessed on May 16, 2020.