Antifungal agents are also called antimycotic agents. They kill or inactivate fungi and are used to treat fungal infections (including yeast infections).

Azole antifungals are a group of fungistatic agents with broad-spectrum activity. They are classified into two groups: the triazoles and the imidazoles.
They inhibit the cytochrome P450 dependent enzyme lanosterol 14-alpha-demethylase, which converts lanosterol to ergosterol, the main sterol in fungal cell membrane. Depletion of ergosterol damages the cell membrane resulting in cell death.
Azole antifungal agents can be used to treat systemic and topical (athlete's foot, ringworm, etc.) fungal infections
Generic names: itraconazole, posaconazole, fluconazole, ketoconazole, clotrimazole, isavuconazonium, miconazole, voriconazole.

Echinocandins are a class of antifungal drugs that target the fungal cell wall. They are lipopeptide molecules that noncompetitively inhibit (1,3) beta-d-glucan synthase enzyme. This enzyme forms glucan, a major component of the fungal cell wall therefore by inhibiting its synthesis fungal cell walls are damaged.
Generic names: caspofungin, anidulafungin, micafungin.

Polyene antifungals bind to ergosterol, the main sterol in the fungal cell membrane, and cause depolarization of the membrane. This increases the membrane permeability and leads to cell death.
They are not absorbed when given orally, so are used to treat fungal infections of the gastrointestinal tract, such as oral thrush. For treatment of systemic fungal infections they need to be administered intravenously.
Generic names: nystatin, amphotericin b

Miscellaneous antifungals
Generic names: griseofulvin, terbinafine, flucytosine

See reference for more information.

Drugs.com. Drug Information Database. Internet. Accessed on October 5, 2016