Published by Roberto Wenk.
Last updated date: December 30, 2015.
Toxic physical or (less commonly) psychological reaction to a therapeutic agent.
The reaction may be predictable, or allergic or idiosyncratic (unpredictable).
An appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention, specific treatment, alteration of the dosage regimen, or withdrawal of the product.