A disease of the immune system due to infection with HIV. HIV destroys the CD4 T lymphocytes (CD4 cells) of the immune system, leaving the body vulnerable to life-threatening infections and cancers. Acquired immunodeficiency syndrome (AIDS) is the most advanced stage of HIV infection. To be diagnosed with AIDS, a person with HIV must have an AIDS-defining condition or have a CD4 count less than 200 cells/mm³.
Defining the condition
Any of a list of illnesses that, when occurring in an HIV-infected person, leads to a diagnosis of AIDS, the most serious stage of HIV infection.
The Centers for Disease Control and Prevention (CDC) published a list of AIDS-defining conditions in 1993. The 26 conditions include candidiasis, cytomegalovirus disease, Kaposi's sarcoma (KS), mycobacterium avium complex, pneumocystis jiroveci pneumonia, recurrent pneumonia, progressive multifocal leukoencephalopathy, pulmonary tuberculosis, invasive cervical cancer, and wasting syndrome.