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Advanced kidney disease

  1. This term predominantly refers to those with late stage 4 and stage 5 chronic kidney diseases (CKD), either on renal replacement therapy, being prepared for this treatment or having opted not to undergo it.

    Stages of chronic kidney disease
    Stage 1. Normal or increased Glomerular Filtration Rate (GFR), with other evidence of kidney damage. GFR > 90 ml/min/1,73m
    Stage 2. Slight decrease in GFR, with other evidence of kidney damage. GFR: 60 - 90 ml/min/1,73m
    Stage 3. Moderate decrease in GFR, with or without other evidence of kidney damage. GFR: 30 - 60 ml/min/1,73m
    Stage 4. Severe decrease in GFR, with or without other evidence of kidney damage. GFR: 15 - 30 ml/min/1,73m.
    Stage 5. Established renal failure. GFR: < 15 ml/min/1,73m.

    Reference: O’Donoghue D, Richards M. end of life care in advanced kidney disease: a framework for implementation. NHS Kidney Care National End of Life Care Progamme. June 2009. Internet. Accessed December 22, 2010. Available at: http://www.endoflifecareforadults.nhs.uk/assets/downloads/EndofLifeCareAKD.pdf. Reid J. The national framework for renal services part two: chronic kidney disease, acute renal failure and end of life care. DH Departament of health . NHS. February 2005 Internet. Accessed December