A transient condition following the administration of alcohol or other psychoactive substance, resulting in disturbances in level of consciousness, cognition, perception, affect or behaviour, or other psychophysiological functions and responses.
Acute intoxication is usually closely related to dose levels. Exceptions to this may occur in individuals with certain underlying organic conditions (e.g. renal or hepatic insufficiency) in whom small doses of a substance may produce a disproportionately severe intoxicating effect. Disinhibition due to social context should also be taken into account.
Acute intoxication is a transient phenomenon. Intensity of intoxication lessens with time, and effects eventually disappear in the absence of further use of the substance. Recovery is therefore complete except where tissue damage or another complication has arisen.
Reference: World Health Organization. The ICD-10 Classification of mental and behavioral Disorders: Clinical descriptions and diagnostic guidelines. Internet. Accessed December 28, 2010. Available at: http://www.who.int/substance_abuse/terminology/ICD10ClinicalDiagnosis.pdf .