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Agonist / antagonist medication

  1. A chemical entity extrinsic to endogenously produced substances that acts on a family of receptors (such as mu, delta and Kappa opiate receptors) in such a fashion that is an agonist or partial agonist on one type of receptor and as antagonist on another.

    See also: agonist, antagonist

    Reference: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Fourth Edition, Text Revision. Washington, DC. American Psychiatric Association. 2000. Page 819


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