Variceal haemorrhage in patients with cirrhosis: 25 mcg/hr for 48 hr (up to 5 days in patients at high risk of re-bleeding).
Acromegaly. Following initial control with SC therapy - depot. Initial: 20 mg 4 wkly. Adjust if required after 3 mth to 10-30 mg 4 wkly. Max: 40 mg 4 wkly.
Secretory neoplasms - SC. Initial: 50 mcg 1-2 times/day, up to 600 mcg/day in 2-4 divided doses based on response. Maintenance - depot 10-30 mg 4 wkly IM
Acromegaly. Initial: 50 mcg 3 times/day, increase if needed. Usual dose: 100-200 mcg 3 times/day. Max: 500 mcg 3 times/day.
Prevention of complications following pancreatic surgery: 100 mcg 3 times/day of a rapid-acting preparation for 7 days, starting at least 1 hr pre-op.
HIV-associated diarrhoea. Initial: 100 mcg 3 times/day. If symptoms are not controlled after 1 wk, increase to 250 mcg 3 times/day.
Secretory neoplasms. Initial: 50 mcg 1-2 times/day, up to 600 mcg/day in 2-4 divided doses based on response
Adverse drug reactions
: local pain at site of injection; anorexia, nausea, vomiting, abdominal pain, bloating, flatulence, loose stools, steatorrhoea; biliary tract abnormalities.
Adapted from CIMS Drug Information System. Internet. Accessed on January 10, 2016.