Peptic ulcer: 1-2 mg 2-3 times/day.
Reversal of neuromuscular blockade: 200 mcg for each 1 mg of neostigmine or 5 mg of pyridostigmine.
Reduction of secretions: Pre-op: 4 mcg/kg via IM administration 30-60 mins before procedure. Intraoperative: 0.1 mg via IV administration, repeat at 2-3 min intervals when needed. Max: 400 mcg/dose.
Peptic ulcer: 0.1-0.2 mg 3-4 times/day.
Adverse drug reactions
: xerostomia, loss of taste, nausea, vomiting, constipation, reduced sweating, urinary hesitancy and retention, blurred vision, cycloplegia, increased ocular tension, tachycardia, palpitation, headache, anxiety, bloated feeling, impotence, skin reactions.
Adapted from CIMS Drug Information System. Internet. Accessed on January 10, 2016.