Cytomegaloviral retinitis 1 g tid as maintenance dose.
Prophylaxis of cytomegaloviral infections in immunocompromised patients 1 g tid.
Cytomegaloviral infections. Initial: 5 mg/kg 12 hrly for 14-21 days, then 5 mg/kg once daily for 7 days/wk or 6 mg/kg once daily for 5 days/wk.
Prophylaxis of cytomegaloviral infections in immunocompromised patients. Initial: 5 mg/kg 12 hrly for 7-14 days, then 5 mg/kg once daily for 7 days/wk or 6 mg/kg once daily for 5 days/wk.
Herpes simplex keratitis - 0.15% gel: Apply 1 drop in the inferior conjunctival sac of the affected eye 5 times/day.
Adverse drug reactions
: haematologic effects (e.g. neutropenia, thrombocytopenia, anaemia, eosinophilia); headache, seizure, coma, confusion, thought disorders, dysphoria, agitation, hallucinations, abnormal dreams/nightmares, nervousness/anxiety, delirium, dizziness, dysaesthesia, asthenia, intention tremor, abnormal reflexes, ataxia, paraesthesia, psychosis, somnolence, obtundation; elevated serum aminotransferase and alkaline phosphatase levels; nausea, vomiting, diarrhoea, anorexia, GI haemorrhage, increased serum creatinine and BUN levels.
Adapted from CIMS Drug Information System. Internet. Accessed on January 10, 2016.