Depression. Initial: 20-30 mg bid or 60 mg once daily, then increase dose in increments of 30 mg/day over 1 wk. Max: 120 mg/day.
Anxiety: 30 or 60 mg once daily. Max: 120 mg/day.
Diabetic neuropathy: 60 mg once daily. Max: 120 mg/day in divided doses.
Fibromyalgia. Initial: 30 mg once daily for 1 wk, then increase to 60 mg once daily.
Adverse drug reactions
: changes in behaviour, suicidal ideation, headache, somnolence, fatigue, dizziness, insomnia, agitation, anxiety, insomnia, lethargy, abnormal dreams, nausea, palpitation, decreased libido, sexual dysfunction, vomiting, constipation, diarrhoea, dyspepsia, abdominal pain.
Adapted from CIMS Drug Information System. Internet. Accessed on January 10, 2016.