Epilepsy - Initial: 100-200 mg once daily or bid, may increase gradually. Maintenance: 0.8-1.2 g/day in divided doses. Max: 2 g/day.
Trigeminal neuralgia - Initial: 100-200 mg bid, may increase gradually. Maintenance: 400-800 mg/day in divided doses. Max: 1.2 g/day.
Prophylaxis of bipolar disorder - Initial: 400 mg/day in divided doses, may increase gradually. Maintenance: 400-600 mg/day in divided doses. Max: 1.6 g/day.
Epilepsy - Max: 250 mg 6 hrly for not more than 7 days.
Adverse drug reactions:
dizziness, drowsiness, ataxia; nausea, vomiting, dry mouth, abdominal pain, anorexia. Diarrhoea or constipation; mild skin reactions, disturbances of cerebellar and oculo-motor function, transient leucopenia, eosinophilia, leucocytosis, thrombocytopaenia, lyphadenopathy, splenomegaly, pneumonitis, abonormalities of liver and kidney function, hyponatraemia, oedema; paraesthesia, headache, arrhythmias and heart block, impotence, male infertility, dystonias and dykinesias w/ asterixis.
CIMS Drug Information System. Internet. Accessed on January 10, 2016.