Tetrahydrocannabinol, a component of marijuana, acts both centrally and peripherally on endogenous cannabinoid receptors; activation of cannabinoid receptors affects serotonin release, increases catecholamines, inhibits parasympathetic activity, and inhibits prostaglandin biosynthesis
The US DEA classifies marijuana as a Schedule 1 substance; schedule I drugs are recognized as having a high potential for abuse with insufficient evidence for safety and efficacy. Marijuana remains classified as an illicit drug by the DEA.
Decrease intraocular pressure, analgesia, antiemetic effects, appetite stimulant
No guidelines exist for dosage ranges
; the drug deteriorates rapidly and its potency is highly variable
Tincture: 5-15 drops or 1-3 drops of fluid extract
Marinol: 5-15 mg/sq meter q2-4hr prn or 2.5-10 mg PO BID
1-3 grains (65-195 mg) cannabis for smoking
See reference for more information.
Adapted from Medscape Drugs & Diseases. Marijuana (Rx). Available at http://reference.medscape.com/drug/cannabis-ganja-marijuana-343687#4. Accessed on September 1, 2016. To view the entire article and all other content on the Medscape Drugs & Diseases site, a free, one-time registration is required.