Smoking cessation: extended release 150 mg once daily for 6 days, then increase to 150 mg twice daily. Duration: 7-12 wk. Max: 300/day.
Depression - Initial: 100 mg twice daily, up to 100 mg 3 times/day after 3 days if needed. Max: 150 mg 3 times/day.
Adverse drug reactions
: nausea, dry mouth, constipation, diarrhoea, anorexia; mouth ulcer; thirst; myalgia, arthralgia; insomnia, dream, abnormality, anxiety, disturbed concentration, dizziness, nervousness, tremor, dysphoria; rhinitis, increased cough, pharyngitis, sinusitis; dyspnoea, epistaxis, agitation, insomnia, tremor, headache, weight loss, vomiting, skin rash.
Adapted from CIMS Drug Information System. Internet. Accessed on January 10, 2016.